ClariTrial | Search Clinical Trials

Status

Phase

26 results for “Arvinas”

Page 1 of 2

Completed

A Study to Learn How a Tablet Compared With an IV Infusion of the Study Medicine Called Vepdegestrant is Taken up Into the Blood in Healthy Adults

Phase 1Healthy Participants

Vepdegestrant (Reference)Vepdegestrant (Test)

Pfizer10 participants2 sites · NetherlandsCompletes May 2025

Compare CT.gov Full analysis →

Completed

Results posted

A Study to Understand the Effect of Itraconazole on the Levels of a Study Medicine Called ARV-471 in Healthy Adults

Phase 1Healthy

vepdegestrantItraconazole

Pfizer12 participants1 site · BelgiumCompletes Apr 2023

Compare CT.gov Full analysis →

Completed

A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants

Phase 1Healthy Participants

VepdegestrantCarbamazepine

Pfizer12 participants1 site · BelgiumCompletes Oct 2023

Compare CT.gov Full analysis →

Active

Results posted

A Study to Learn About the Vepdegestrant (ARV-471, PF-07850327) in People With ER+/HER2- Locally Advanced or Metastatic Breast Cancer (BC)

Phase 1Breast Neoplasms

vepdegestrant

Pfizer6 participants3 sites · JapanCompletes May 2023

Compare CT.gov Full analysis →

Active

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Phase 1Phase 2Breast Cancer

vepdegestrantSamuraciclib

Pfizer11 participants21 sites · United States, Belgium, FranceCompletes Apr 2026

Compare CT.gov Full analysis →

Completed

A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam

Phase 1Healthy Participants

MidazolamVepdegestrant

Pfizer15 participants1 site · BelgiumCompletes Apr 2024

Compare CT.gov Full analysis →

Completed

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Phase 1Healthy

[phenyl-14C]ARV-471[oxoisoindolin-14C]ARV-471

Pfizer12 participants1 site · United StatesCompletes Jul 2023

Compare CT.gov Full analysis →

Active

A Study to Learn About Vepdegestrant When Given With PF-07220060 to People With Advanced or Metastatic Breast Cancer.

Phase 1Phase 2Breast Cancer

vepdegestrantPF-07220060

Pfizer71 participants58 sites · United States, Belgium, CanadaCompletes Sep 2025

Compare CT.gov Full analysis →

Completed

A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE®) in Patients With ER+/HER2- Locally Advanced or Metastatic Breast Cancer

Phase 1Phase 2Breast Cancer

ARV-471ARV-471 in combination with palbociclib (IBRANCE®)

Arvinas Estrogen Receptor, Inc.217 participants16 sites · United StatesCompletes Sep 2024

Compare CT.gov Full analysis →

Completed

Trial of ARV-110 and Abiraterone in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Phase 1Prostate Cancer Metastatic

ARV-110 in Combination with Abiraterone

Arvinas Androgen Receptor, Inc.45 participants18 sites · United States, Canada, FranceCompletes Jul 2024

Compare CT.gov Full analysis →

Active

Vepdegestrant (ARV-471/PF-07850327) + Palbociclib vs Letrozole + Palbociclib in ER(+)/HER2(-) Advanced Breast Cancer

Phase 3Breast Cancer

Vepdegestrant (ARV-471/PF-07850327)PalbociclibLetrozole+1 more

Pfizer59 participants29 sites · United States, Australia, BrazilCompletes Dec 2026

Compare CT.gov Full analysis →

Completed

Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer

Phase 1Phase 2Prostate Cancer Metastatic

ARV-110

Arvinas Inc.248 participants54 sites · United StatesCompletes Apr 2024

Compare CT.gov Full analysis →

Completed

A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant

Phase 1Healthy

vepdegestrantesomeprazole

Pfizer12 participants1 site · United StatesCompletes May 2024

Compare CT.gov Full analysis →

Active

Results posted

A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer

Phase 3Advanced Breast Cancer

ARV-471Fulvestrant

Pfizer624 participants312 sites · United States, Argentina, AustraliaCompletes Jan 2025

Compare CT.gov Full analysis →

Completed

A Study to Learn How Different Tablets of the Study Medicine Vepdegestrant Are Taken up Into the Blood in Healthy Adults

Phase 1Healthy

single dose of vepdegestrant as tablet formulation (Treatment A)single dose of vepdegestrant as tablet formulation (Treatment B)

Pfizer12 participants1 site · BelgiumCompletes Feb 2025

Compare CT.gov Full analysis →

1–15 of 26

Explore/Arvinas

Status

Phase

26 results for “Arvinas”

Page 1 of 2

Completed

A Study to Learn How a Tablet Compared With an IV Infusion of the Study Medicine Called Vepdegestrant is Taken up Into the Blood in Healthy Adults

Phase 1Healthy Participants

Vepdegestrant (Reference)Vepdegestrant (Test)

Pfizer10 participants2 sites · NetherlandsCompletes May 2025

Compare CT.gov Full analysis →

Completed

Results posted

A Study to Understand the Effect of Itraconazole on the Levels of a Study Medicine Called ARV-471 in Healthy Adults

Phase 1Healthy

vepdegestrantItraconazole

Pfizer12 participants1 site · BelgiumCompletes Apr 2023

Compare CT.gov Full analysis →

Completed

A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants

Phase 1Healthy Participants

VepdegestrantCarbamazepine

Pfizer12 participants1 site · BelgiumCompletes Oct 2023

Compare CT.gov Full analysis →

Active

Results posted

A Study to Learn About the Vepdegestrant (ARV-471, PF-07850327) in People With ER+/HER2- Locally Advanced or Metastatic Breast Cancer (BC)

Phase 1Breast Neoplasms

vepdegestrant

Pfizer6 participants3 sites · JapanCompletes May 2023

Compare CT.gov Full analysis →

Active

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Phase 1Phase 2Breast Cancer

vepdegestrantSamuraciclib

Pfizer11 participants21 sites · United States, Belgium, FranceCompletes Apr 2026

Compare CT.gov Full analysis →

Completed

A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam

Phase 1Healthy Participants

MidazolamVepdegestrant

Pfizer15 participants1 site · BelgiumCompletes Apr 2024

Compare CT.gov Full analysis →

Completed

A Study to Understand How the Study Medicine Called ARV-471 is Processed in Healthy Adults

Phase 1Healthy

[phenyl-14C]ARV-471[oxoisoindolin-14C]ARV-471

Pfizer12 participants1 site · United StatesCompletes Jul 2023

Compare CT.gov Full analysis →

Active

A Study to Learn About Vepdegestrant When Given With PF-07220060 to People With Advanced or Metastatic Breast Cancer.

Phase 1Phase 2Breast Cancer

vepdegestrantPF-07220060

Pfizer71 participants58 sites · United States, Belgium, CanadaCompletes Sep 2025

Compare CT.gov Full analysis →

Completed

A Phase 1/2 Trial of ARV-471 Alone and in Combination With Palbociclib (IBRANCE®) in Patients With ER+/HER2- Locally Advanced or Metastatic Breast Cancer

Phase 1Phase 2Breast Cancer

ARV-471ARV-471 in combination with palbociclib (IBRANCE®)

Arvinas Estrogen Receptor, Inc.217 participants16 sites · United StatesCompletes Sep 2024

Compare CT.gov Full analysis →

Completed

Trial of ARV-110 and Abiraterone in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Phase 1Prostate Cancer Metastatic

ARV-110 in Combination with Abiraterone

Arvinas Androgen Receptor, Inc.45 participants18 sites · United States, Canada, FranceCompletes Jul 2024

Compare CT.gov Full analysis →

Active

Vepdegestrant (ARV-471/PF-07850327) + Palbociclib vs Letrozole + Palbociclib in ER(+)/HER2(-) Advanced Breast Cancer

Phase 3Breast Cancer

Vepdegestrant (ARV-471/PF-07850327)PalbociclibLetrozole+1 more

Pfizer59 participants29 sites · United States, Australia, BrazilCompletes Dec 2026

Compare CT.gov Full analysis →

Completed

Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancer

Phase 1Phase 2Prostate Cancer Metastatic

ARV-110

Arvinas Inc.248 participants54 sites · United StatesCompletes Apr 2024

Compare CT.gov Full analysis →

Completed

A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant

Phase 1Healthy

vepdegestrantesomeprazole

Pfizer12 participants1 site · United StatesCompletes May 2024

Compare CT.gov Full analysis →

Active

Results posted

A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer

Phase 3Advanced Breast Cancer

ARV-471Fulvestrant

Pfizer624 participants312 sites · United States, Argentina, AustraliaCompletes Jan 2025

Compare CT.gov Full analysis →

Completed

A Study to Learn How Different Tablets of the Study Medicine Vepdegestrant Are Taken up Into the Blood in Healthy Adults

Phase 1Healthy

single dose of vepdegestrant as tablet formulation (Treatment A)single dose of vepdegestrant as tablet formulation (Treatment B)

Pfizer12 participants1 site · BelgiumCompletes Feb 2025

Compare CT.gov Full analysis →

1–15 of 26